Targeting Chemokines in Aortic Aneurysm

Targeting chemokines in aortic aneurysm: could this be key to a novel therapy for a common problem?

Drug Therapy for Small Abdominal Aortic Aneurysm

Dear Editor,Abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. The incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positive...

Aortic Valve replacement with Reduction Aortoplasty with Mesh Prosthesis in 75 years old with Sever aortic Regurgitation with Aortic Aneurysm

Although classic and standard procedure for patients with ascending Aorta aneurysm with Sever aortic Regurgitation is Bentall surgery but in some selected cases this complex surgery was not performed with different reason like advanced age and coexisting comorbidity involving renal and hepatic and lung Function. In our cases 75 years old man with chronic renal failure ( Cr= 3.2 ) who was known ...

Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm

MicroRNAs (miRNAs) are deregulated in various vascular ailments including abdominal aortic aneurysm (AAA). MiR-103 is involved in vascular, metabolic, and malignant diseases, but whether it participates in the pathogenesis of AAA remains elusive. ADAM10 plays a vital role in the formation of aneurysm, but whether miRs modulate its activity during AAA formation is totally unknown. In this study,...

Aortic Aneurysm

Aortic aneurysms can be classified into thoracic & abdominal aortic aneurysm with different clinical features, diagnostic characteristics and management. If the growth occurs continuously, it can result in bursting of the artery and bleeding, a condition termed aortic dissection, which is considered a catastrophic fatal condition. Abdominal aortic aneurysms are generally caused due to infection...